Predicted data is generated using the us environmental protection agencys episuite. Buy 3chloro phenyl methanesulfonyl chloride cas 24974730, a biochemical for proteomics research, from santa cruz. Methanesulfonyl chloride 124630 msds report, methanesulfonyl chloride msds safety technical specifications search, methanesulfonyl chloride safety information specifications ect. After stirring for 2 hours, gas evolution ceases, and a clear, colorless solution of sodium methanesulfinate note 3 is obtained. About 14% of these are dyestuff intermediates, % are chloride, and 54% are pharmaceutical intermediates. Eye contact rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Cas 124630, ec number 2047061, chemical formula ch. Sigmaaldrich offers a number of methanesulfonyl chloride products. A typical synthesis is to treat methanesulfonyl chloride with potassium fluoride or potassium bifluoride in water and then steam distill the product out. Wholebody exposure chambers were constructed of perspex and had an internal volume of 115 l.
The slightly exothermic reaction is accompanied by the evolution of carbon dioxide. The combined organics were washed with h2o 20 ml, brine 20 ml, dried. Your new online msds binder is a place for you to store the material safety data sheets you need to deploy. Information provided on methanesulfonyl chloride 124630 is for reference only and is subject to change.
Additional information 96hr lc50 guppy static with neutralized msc. Methanesulfonyl chloride is mainly used to give methanesulfonates by its reaction with alcohols in the presence of a nonnucleophilic base. Burning sodium perchlorate may produce chlorine, chlorine dioxide, hydrogen chloride, and oxides of nitrogen as well as mixtures with any other compounds involved in the combustion. Information for methanesulfonyl chloride 124630 including methanesulfonyl chloride cas no 124630, methanesulfonyl chloride suppliers, methanesulfonyl chloride manufacturers, related products of methanesulfonyl chloride. Synthesis of methanesulfonyl chloride msc from methane. Methanesulfonyl chloride, also known as mesyl chloride, can be used to generate the elusive molecule sulfene and to make methanesulfonates. Methanesulfonyl chloride, methanesulfonyl chloride supplier, methanesulfonyl chloride distributor, cas 124630, methanesulfonyl chloride manufacturer, methanesulfonyl chloride wholesale. It undergoes decomposition on heating to liberate additional toxic fumes of fluorides and sulfur oxides so x. Methanesulfonyl chloride ch3clo2s cid 31297 structure, chemical names, physical and. Methanesulfonyl chloride using the organic pseudoelement symbol ms for the methanesulfonyl or mesyl group ch3so2, it is frequently abbreviated mscl in reaction schemes or equations. Als environmental does not sell chemicals, but offers analytical lab testing to determine the presence of various elements and chemical compounds. A single example of a secondary alcohol produced the chloride in 50% yield. Ungraded products supplied by spectrum are indicative of a grade suitable for general industrial use or research purposes and typically are not suitable for human consumption or therapeutic use. Methanesulfonyl chloride revision date 26jan2018 general advice immediate medical attention is required.
This does not prevent hcl formation by a catalytic mechanism, but under normal conditions methanesulfonyl chloride is quite unreactive argonne report anldis001, october 2000. Synthesis of methanesulfonyl chloride msc from methane and. Thionyl chloride is on the hazardous substance list because. The reaction of methanesulfonyl chloride with alcohols in. Sds of methanesulfonyl chloride, safety data sheets, cas. For a more comprehensive list of citations to this article, users are encouraged to perform a search inscifinder the reaction of 23sydnonylphenylmethanol with sulfonyl chlorides. Use this link for bookmarking this species for future reference. Methanesulfonyl chloride cas 124630 msds guidechem. Experimental work at argonne national laboratory has determined that there is essentially no hcl gas formation. Methanesulfonyl chloride is a precursor to many compounds because it is highly reactive. Emergency preparedness and response safety and health. Reach registration 172120042741640000 sds compliant with regulations. Safety data sheet methanesulfonyl chloride date prepared. A wide variety of methanesulfonyl chloride options are available to you.
Methanesulfonyl chloride can be used as catalyst, chlorinating agent, firming agent, stabilizer or as an intermediate for dyes, pharmaceuticals and pesticides. Citation data is made available by participants in crossrefs citedby linking service. Information should be used as a guide only, as the information is only current at the date of publication. The mixture was quenched with h2o 10 ml and extracted with dcm 2 x 20 ml. Methanesulfonyl chloride vaillancourt major reference works. Methanesulfonyl chloride or mesyl chloride abbreviation. One reagent lane fair lawn, nj 07410 for information in north america, call. Articles of methanesulfonyl chloride are included as well. Show this safety data sheet to the doctor in attendance. Chemical compatibility chart the attached information has been prepared in good faith by rapra technology limited and other sources. Methanesulfonyl chloride supplier distributor cas 124630.
Trichloromethyl methyl sulfide d 3 was found to be one of the intermediates in this reaction. Under the authority of the federal advisory committee act faca p. Methanesulfonyl chloride information about methanesulfonyl chloride is for educational purposes only. The reaction mixture was stirred at 0 c for 30 min, then was allowed to warm to rt over 2 h.
Methanesulfonyl chloride is the reagent used to convert alcohols into alkyl mesylates. Perchloric acid, sodium salt in aqueous solution, sp product code. Methanesulfonyl chloride mesyl chloride is a compound containing asulfonyl chloride used to make methanesulfonates and to generate sulfene. Using the organic pseudoelement symbol ms for the methanesulfonyl or mesyl group ch 3 so 2, it is frequently abbreviated mscl in reaction schemes or equations. Methanesulfonyl chloride msc1 is a versatile reagent that can be used to introduce mesyl groups ch3so22 via.
Methylene chloride please ensure that this msds is given to, and explained to people using this product. Methanesulfonyl chlorided 3 was obtained in 52% yield, and a small amount of dimethyl sulfoned 6 was also isolated. Sep 11, 2014 register now and get a free online msds binder. Methanesulfonyl chloride 124630 msds, safety technical. Sciencemadness discussion board methanesulfonic acid. Groups of five male and five female spraguedawley rats were exposed to methanesulfonyl chloride at 0, 20, 28, or 54 ppm analytic concentrations for 4 h, followed by a 14day observation period pennwalt corporation 1987. Methanesulfonyl chloride reacts vigorously with water, steam, alkali, methylformamide. In the case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Other companies are charging thousands of dollars to set up accounts and give you access to their msds online database.
Methanesulfonyl chloride cas no 124630 manufacturers. After stirring for 2 hours, gas evolution ceases, and a clear, colorless solution of. It is a colourless liquid that dissolves in polar organic solvents but is. The mechanism of action of this compound includes the potentiation of glucose uptake demonstrated in 3t3l1 adipocytes as well as the stimulation. Methane is transformed selectively to methanesulfonyl chloride at low temperature by liquidphase reaction of methane with so 2cl 2 in the presence of a free radical initiator and a promoter using 100% h 2so 4 as the solvent. Methanesulfonyl chloride mesyl chloride is an organosulfur compound with the formula ch 3 so 2 cl. Mscl is the compound obtained when the hydroxy group in the molecule of methanesulfonic acid is replaced with a chlorine atom. Methanesulfonyl chloride prices,suppliers methanesulfonyl. Methanesulfonic acid chloridecas no124630molecular formula.
These are common byproducts of combustion and are likely to be serious health concern. One reagent lane fair lawn, nj 07410 for information in north america. These methanesulfonyl chloride manufacturing companies are delivering best quality products to the clients on time. Sultams obtained as a mixture of two isomers are separable by silica gel column. It is a colourless liquid that dissolves in polar organic solvents but is reactive toward water, alcohols, and many amines. Methanesulfonyl chloride msds material safety data sheet or sds, coa and coq, dossiers. Buy methanesulfonyl chloride d3,c cas 1216581019, a biochemical for proteomics research, from santa cruz. There are a wide variety of direct reading instruments and analytical sampling. Harmful to aquatic life with long lasting effects hazardous to the aquatic. Als environmental provides no warranty, expressed or implied, as to the accuracy, reliability or completeness of furnished data. Ac125640000, ac125640010, ac125640050, ac12564, ac125642500 synonyms. In case of more serious fires, also alcoholresistant foam and water spray. Als environmental is a laboratory testing network and is not affiliated with the u.
Listing here the database of methanesulfonyl chloride cas no 124630, methanesulfonyl chloride manufacturers, suppliers and exporters. Mesyl chloride, methyl sulfonyl chloride cas number 124630. Find msds or sds, a coa, data sheets and more information. Methanesulfonyl chloride mesyl chloride is an organosulfur compound with the formula ch3so2cl.
Sds of methanesulfonyl chloride, safety data sheets, cas 124630. Emits toxic fumes of chloride and oxides of sulfur when heated to decomposition. In the case of contact with eyes, rinse immediately with plenty of water and seek medical. Applicationsmethanesulfonates the main use of methanesulfonyl chloride is the formation of methanesulfonates from alcohols in the presence of a. Alcohol to mesylate methanesulfonyl chloride meso2cl. Buy methanesulfonyl chlorided3,c cas 1216581019, a biochemical for proteomics research, from santa cruz. There is no warranty of accuracy or completeness of any information contained herein. Development and validation of a gcms with sim method for the. Reacts explosively with dimethyl sulfoxide buckley, a. Methanesulfonyl chloride is used as a reagent for conversion of alcohols to mesylate esters such as methanesulfonate, which is an intermediate in substitution reactions, elimination reactions, reductions, and rearrangement reactions viz.
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